What are the precautions for using budesonide and formoterol powder for inhalation?

Generally, budesonide/formoterol powder for inhalation is a compound anti-asthma medication used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Proper use and safety precautions should be observed during therapy. Key considerations include mastering the correct inhalation technique, preventing local adverse reactions, adjusting dosage according to medical advice, monitoring the risk of respiratory infections, and avoiding abrupt discontinuation of the drug. A detailed analysis is as follows:

1. Master the correct inhalation technique: Shake the inhaler well before use. After exhaling deeply, place the mouthpiece firmly between your lips and inhale slowly and deeply while pressing down to release the medication. Hold your breath for 5–10 seconds after inhalation, then exhale slowly. Rinse your mouth with water immediately after inhalation and spit it out to prevent discomfort caused by drug residue in the oral cavity.

2. Prevent local adverse reactions: Long-term use may lead to oral candidiasis, manifested as white patches on the oral mucosa and dry mouth, or hoarseness. Performing proper mouth rinsing after each inhalation can reduce these risks. If infection occurs, antifungal treatment should be administered under a physician’s guidance.

3. Adjust dosage as directed by a physician: This medication can be used either for maintenance therapy or reliever therapy, and the dosage should be individualized based on disease severity. Do not increase the dose on your own to achieve rapid relief, nor reduce the dose or stop using it without authorization when symptoms improve.

4. Monitor the risk of respiratory infections: Budesonide may slightly affect local immune function. Patients on long-term therapy should watch for signs of respiratory infection, such as worsening cough, increased purulent sputum, or fever.

5. Avoid abrupt discontinuation: Suddenly stopping the medication after long-term use may trigger acute exacerbations of asthma or COPD, leading to symptoms such as chest tightness and worsened wheezing. If discontinuation is necessary, the dose should be tapered gradually under medical supervision.

Regular follow-up visits are required during treatment, allowing the physician to evaluate therapeutic response and adjust the regimen accordingly. Always carry the medication with you, and take care to protect the device from strong impacts when traveling. Additionally, maintain smoking cessation and avoid irritants such as dust and smoke to support long-term respiratory health.