How to quickly lower elevated transaminase levels in hepatitis B

Dec 03, 2025 Source: Cainiu Health
Dr. Gao Jun
Introduction
In general, elevated transaminase levels in hepatitis B patients may be caused by excessive fatigue, consumption of spicy foods, active replication of the hepatitis B virus, fatty liver disease concurrent with hepatitis B, or hepatitis B accompanied by cholecystitis. Patients can choose appropriate management approaches such as lifestyle modifications, medication, or surgical treatment based on their specific conditions. Liver protection should be incorporated into daily routines, including maintaining a light diet and regular作息 (daily schedule).

Generally, elevated transaminase levels in hepatitis B patients may be caused by excessive fatigue, spicy diet, active hepatitis B virus replication, fatty liver combined with hepatitis B, or hepatitis B accompanied by cholecystitis. Patients can choose appropriate management methods such as lifestyle adjustments, medication, or surgical treatment based on their specific conditions. Detailed analysis is as follows:

1. Excessive Fatigue

Prolonged熬夜 or heavy physical labor can impair liver cell repair, leading to the release of transaminases into the bloodstream. Adjust daily routines promptly by ensuring at least 7 hours of sleep each night, suspending high-intensity work, and engaging primarily in light exercises such as walking.

2. Spicy Diet

Spicy foods irritate the gastrointestinal mucosa, indirectly increasing the metabolic burden on the liver and causing elevated transaminase levels. Avoid consuming chili peppers, Sichuan peppercorns, and similar foods. Focus on a bland, easily digestible diet including porridge and vegetables, and drink plenty of warm water.

3. Active Hepatitis B Virus Replication

Massive viral replication damages liver cells, resulting in leakage of intracellular transaminases into the blood. Under medical guidance, patients may take entecavir tablets, tenofovir alafenamide fumarate tablets, or lamivudine tablets, with regular monitoring of viral load.

4. Fatty Liver Combined with Hepatitis B

Fat accumulation in hepatocytes synergistically damages the liver together with the hepatitis B virus, further elevating transaminase levels. Reduce dietary fat intake and increase aerobic exercise. As directed by a physician, medications such as silybin capsules, polyene phosphatidylcholine capsules, or diammonium glycyrrhizinate enteric-coated capsules may be used.

5. Hepatitis B with Cholecystitis

Inflammation of the gallbladder spreads to the liver, impairing bile excretion and inducing liver cell injury. Under medical supervision, ursodeoxycholic acid capsules, anti-inflammatory and cholagogue tablets, or cefuroxime axetil tablets may be prescribed. In severe cases, laparoscopic cholecystectomy may be required.

Liver protection requires consistent daily efforts, including maintaining a light diet, regular作息, strict abstinence from alcohol, and avoiding misuse of medications. Patients with hepatitis B should undergo regular follow-up tests for liver function and viral markers, promptly address any abnormalities, actively avoid liver-damaging factors, and safeguard liver health.