Is it good to use an adenovirus vector for the third dose?

Generally, whether it is appropriate to receive the third dose of an adenovirus vector vaccine depends on individual health status and previous vaccination history. The specific analysis is as follows:

Individuals who are in good health without serious underlying medical conditions, who did not experience allergic or other adverse reactions after the first two doses of the adenovirus vector vaccine, and whose second dose was administered at least six months ago may receive the third dose. These individuals typically have a well-tolerated immune response to the vaccine, which can effectively boost antibody levels and enhance protection against the virus. This group particularly includes immunocompetent adults and individuals in key positions requiring enhanced immunity.

People who are allergic to components of the adenovirus vector vaccine or who previously experienced severe adverse reactions such as serious rashes or difficulty breathing after receiving similar vaccines should not be vaccinated. Individuals currently experiencing fever, acute illness, uncontrolled epilepsy, severe neurological disorders, malignant tumors, or other serious conditions should postpone vaccination. They may consider vaccination only after their condition has stabilized or the disease is under control, following a medical evaluation to determine suitability.

After vaccination, keep the injection site clean and dry to prevent infection, and avoid getting it wet. Avoid strenuous exercise on the day of vaccination, get adequate rest, and drink plenty of warm water to promote metabolism. Maintain a light diet and avoid spicy or irritating foods. If mild local reactions such as redness or pain occur, no special treatment is needed—they usually resolve spontaneously within 1–2 days. Seek medical attention promptly if symptoms worsen.