How long does it take for transaminase levels to decrease from 96 to 40?

Dec 03, 2025 Source: Cainiu Health
Dr. Huang Yuhong
Introduction
If elevated transaminase levels are caused by temporary factors such as staying up late, alcohol consumption, or taking medications that damage the liver, most people can reduce their levels to 40 within 1–2 weeks by promptly adjusting lifestyle habits (stopping alcohol use, maintaining regular作息 should be translated as "sleep schedule"), discontinuing hepatotoxic drugs) and using liver-protective medications. In such cases, liver damage is mild, and recovery is relatively rapid once the triggering factors are removed. Regular follow-up tests can monitor changes in these indicators.

Under normal circumstances, it takes 1–4 weeks for transaminase levels to decrease from 96 to 40. The exact duration varies depending on the underlying cause and intervention methods. If concerned, it is advisable to seek medical consultation early. Detailed analysis is as follows:

If the elevated transaminase levels are due to short-term factors such as staying up late, alcohol consumption, or taking hepatotoxic medications, promptly adjusting lifestyle habits (abstaining from alcohol, maintaining regular sleep patterns, discontinuing liver-damaging drugs) along with using liver-protective medications can reduce levels to 40 within 1–2 weeks for most people. In such cases, liver damage is mild, and recovery is relatively fast once triggers are removed. Regular follow-up tests can monitor changes in these indicators.

If the elevation is caused by chronic liver diseases such as viral hepatitis or fatty liver disease, treatment must first target the underlying cause (e.g., antiviral therapy, lipid control), supplemented by liver-protective measures. It may take 3–4 weeks for levels to drop to 40. In these cases, ongoing liver injury exists, requiring standardized treatment to manage the condition. The recovery period is relatively longer, and full-course interventions should be completed according to medical advice.

After detecting elevated transaminase levels, it is essential to first identify the cause and then implement targeted measures. During treatment, liver function should be regularly rechecked to monitor the decline in indicators. Maintaining a light diet and avoiding fatigue and behaviors that harm the liver will support liver recovery.