How long should a breastfeeding mother wait to nurse after taking Compound Paracetamol and Amantadine Capsules for a fever?

Dec 04, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
In general, after taking Compound Paracetamol and Amantadine Hydrochloride Capsules during lactation, it is recommended to wait 48 hours after discontinuation before resuming breastfeeding. The exact timing should be adjusted based on the dosage taken and individual metabolic conditions. During the period of interrupted breastfeeding, breasts should be regularly emptied using a breast pump to maintain milk production. Adequate warmth and rest should also be ensured to support physical recovery. Before resuming breastfeeding, observe the infant's mental state and well-being.

Generally, after taking Compound Paracetamol and Amantadine Hydrochloride Capsules during lactation, it is recommended to discontinue breastfeeding for 48 hours before resuming. The exact duration should be adjusted based on the dosage taken and individual metabolic conditions.

Compound Paracetamol and Amantadine Hydrochloride Capsules contain ingredients such as paracetamol and chlorpheniramine maleate, some of which may pass into breast milk and potentially affect the infant, especially newborns whose liver and kidney functions are not yet fully developed, requiring avoidance of exposure to residual medication. Continuing breastfeeding during medication may lead to infant drowsiness, reduced appetite, or other adverse effects; therefore, breastfeeding should be temporarily suspended while taking the drug.

After taking the medication, drink plenty of water to promote drug metabolism and excretion. Follow the dosage instructions on the label or as prescribed by a physician strictly to avoid excessive intake, which could prolong the metabolism time. Lactating women vary in metabolic rates—those who are younger and without underlying medical conditions typically metabolize the drug faster, with most of the medication cleared from the body within 48 hours after discontinuation. Individuals with slower metabolism may need to extend the pause to 72 hours to ensure that the drug concentration in breast milk drops to a safe level.

During the period when breastfeeding is paused, use a breast pump regularly to empty the breasts and maintain milk production. Adequate warmth and rest should also be ensured to support physical recovery. Before resuming breastfeeding, observe the baby's mental state and confirm there are no abnormalities before returning to normal nursing.

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