How many hours after drinking red wine can one drink coffee?

Dec 08, 2025 Source: Cainiu Health
Dr. Huang Yuhong
Introduction
Wait at least 4–6 hours after drinking red wine before consuming coffee. The alcohol in red wine and the caffeine in coffee can have combined stimulating effects on the cardiovascular and nervous systems. Consuming them close together may cause discomfort, so sufficient time should be allowed for metabolism. Alcohol dilates blood vessels and depresses the central nervous system, whereas caffeine constricts blood vessels and stimulates the central nervous system.

Wait at least 4–6 hours after drinking red wine before consuming coffee. The alcohol in red wine and the caffeine in coffee can have a combined stimulating effect on the cardiovascular and nervous systems. Consuming them too close together may cause discomfort, so sufficient time should be allowed for metabolism.

Alcohol dilates blood vessels and suppresses the central nervous system, while caffeine constricts blood vessels and stimulates the central nervous system. Their effects are opposing, and taking them shortly after each other can increase stress on the cardiovascular system, potentially causing palpitations, dizziness, and blood pressure fluctuations—especially posing higher risks for individuals with hypertension.

The body requires time to fully metabolize alcohol, typically processing about 10–15 milliliters per hour. A moderate amount of red wine usually takes 4–6 hours to be mostly metabolized. Drinking coffee after this interval helps prevent simultaneous interactions between the two substances, reducing stimulation to the nervous and cardiovascular systems.

After drinking red wine, you may drink warm water to promote metabolism. Avoid intense physical activity during this period. Wait until you are fully alert and the alcohol has been metabolized before drinking coffee. Control your intake of both red wine and coffee to avoid excessive consumption, and always consider your personal health condition, maintaining an appropriate time gap between drinks.

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