What should I do if a lung nodule is detected during evaluation for cough?
Cough leading to the discovery of pulmonary micro-nodules requires appropriate management, including determining nodule characteristics, evaluating the relationship between cough and nodules, following standardized follow-up protocols, adjusting lifestyle, and implementing targeted interventions. Most micro-nodules are likely benign, so excessive anxiety is unnecessary. However, if nodules have irregular shapes, increase in diameter, or if cough is accompanied by hemoptysis or weight loss, prompt medical evaluation is recommended.
1. Determine nodule characteristics: Use enhanced chest CT scans and tumor marker tests to differentiate benign nodules—such as inflammatory hyperplasia or fibrotic foci—from those with malignant potential. This provides a basis for subsequent management and helps prevent unnecessary interventions.
2. Evaluate the association with cough: Assess whether the cough is caused by the nodule. If the nodule irritates the airway or is associated with inflammation, concurrent targeted treatment is needed. If the cough stems from independent respiratory conditions such as allergies or infection, separate interventions should be applied.

3. Follow standardized follow-up protocols: Benign micro-nodules typically require CT re-examination every 6–12 months to monitor changes in size and morphology. If no abnormalities are detected, the follow-up interval may gradually be extended, avoiding both excessive testing and missing signs of malignant transformation.
4. Adjust lifestyle: Quit smoking and avoid secondhand smoke and dusty environments to reduce respiratory irritation. Maintain regular sleep patterns to boost immunity, and avoid staying up late or overexertion, which may increase the risk of nodule progression or worsened inflammation.
5. Implement targeted interventions: Inflammatory nodules may be treated with anti-inflammatory medications under medical supervision, followed by re-evaluation. Nodules suspected of malignancy or showing signs of malignant change require further biopsy or surgical excision to prevent delayed diagnosis and treatment.
Treatment must strictly follow medical advice. Benign nodules are primarily managed through observation and follow-up, while inflammatory nodules require symptomatic medication. For supportive care, ensure indoor ventilation, drink plenty of water to relieve cough, maintain a light and easily digestible diet, avoid spicy or irritating foods, and engage in moderate exercise regularly to improve cardiopulmonary function.