Can vitamin B2 and B6 be taken long-term?

Under normal circumstances, vitamin B2 and B6 can be taken long-term within the recommended dosage. However, prolonged use in excessive amounts or in individuals with specific constitutions may cause adverse effects. If in doubt, it is advisable to supplement appropriately according to individual needs. Detailed analysis is as follows:

Vitamin B2 and B6 are both water-soluble vitamins that the human body cannot store for long periods; excess amounts are excreted in urine. Long-term supplementation at normal doses is generally considered safe. Both vitamins play important roles in metabolic processes and regulation of nervous system functions. Appropriate long-term intake helps maintain normal bodily functions and is particularly beneficial for individuals with unbalanced diets or those in special physiological stages.

However, long-term excessive intake may pose health risks. Excess vitamin B6 may lead to peripheral neuropathy, causing symptoms such as numbness and abnormal sensations in the hands and feet. Excessive vitamin B2 may result in yellow discoloration of urine and skin itching. Individuals with pre-existing liver or kidney conditions should be especially cautious, as long-term supplementation may increase the metabolic burden on these organs.

Supplementation should follow the recommended dosages, and self-increasing of dosage should be avoided. It is preferable to obtain these vitamins through a regular diet—including meat, vegetables, and grains—and consider supplements only when dietary intake is insufficient.