What medications can be taken for primary premature ejaculation?
Dec 09, 2025
Source: Cainiu Health
Dr. Cao Zhiqiang
Introduction
Primary premature ejaculation can be treated with medications such as dapoxetine hydrochloride tablets, sertraline tablets, paroxetine tablets, Jin Suo Gu Jing Wan, or Wuzi Yanzong Wan. The appropriate medication should be selected based on the individual patient's condition to avoid blind use of drugs. If premature ejaculation persistently affects quality of life or is accompanied by other urogenital discomforts, timely medical consultation is recommended.
Primary premature ejaculation can be treated with medications such as dapoxetine hydrochloride tablets, sertraline tablets, paroxetine tablets, Jin Suo Gu Jing Wan, and Wu Zi Yan Zong Wan. The appropriate medication should be selected based on individual patient conditions to avoid blind use of drugs. If premature ejaculation persistently affects quality of life or is accompanied by other urogenital discomforts, timely medical consultation is recommended.
1. Dapoxetine Hydrochloride Tablets: An oral Western medicine that works by regulating neurotransmitter balance to prolong the ejaculatory latency period. It acts quickly and is rapidly metabolized, making it suitable for patients with primary premature ejaculation to improve ejaculatory control. It must be used under professional guidance.
2. Sertraline Tablets: An oral Western medicine originally used for treating depression but clinically applied also in premature ejaculation management. By inhibiting reuptake of neurotransmitters, it helps extend ejaculation time and is particularly suitable for patients experiencing anxiety-related premature ejaculation.
3. Paroxetine Tablets: An oral Western medicine belonging to the selective serotonin reuptake inhibitors (SSRIs) class. It regulates neural functions related to the ejaculatory reflex and helps improve rapid ejaculation in patients with premature ejaculation. Dosage adjustment should be gradual to allow proper adaptation.
4. Jin Suo Gu Jing Wan: A traditional Chinese patent medicine in pill form composed of ingredients such as Astragalus complanatus (Shayuanzi) and Euryale ferox (Qianshi). It functions to strengthen kidney function and consolidate essence, making it suitable for primary premature ejaculation caused by kidney deficiency. It helps alleviate symptoms such as loss of ejaculatory control and soreness of the lower back and knees.
5. Wu Zi Yan Zong Wan: A traditional Chinese patent medicine containing herbs like Lycium barbarum (Gouqizi) and Cuscuta chinensis (Tusizi). It nourishes the kidneys and enriches essence, commonly used for premature ejaculation due to kidney deficiency and depletion of essence. It helps regulate reproductive system function and enhance ejaculatory control.
During treatment, patients should maintain regular sleep patterns and avoid staying up late, reduce intake of spicy, stimulating foods and alcohol, engage in moderate physical exercise to improve physical fitness, maintain emotional stability to prevent anxiety, and emphasize communication with their partner to enhance therapeutic outcomes.
