Is pulmonary fibrosis the same as pulmonary amyloidosis?

Generally, pulmonary fibrosis and pulmonary amyloidosis are different conditions with distinct causes, pathological mechanisms, and treatment approaches. They are separate diseases. If there is any uncertainty, professional medical evaluation is recommended to establish an accurate diagnosis. The detailed analysis is as follows:

Pulmonary fibrosis primarily involves lung tissue damage followed by abnormal repair processes that lead to excessive proliferation of fibrous tissue, which replaces normal alveolar structures and impairs gas exchange. Common triggers include infections, autoimmune diseases, and environmental exposures. Symptoms typically include progressive shortness of breath and dry cough, with the disease usually following a chronic, progressive course.

Pulmonary amyloidosis, on the other hand, is caused by the abnormal deposition of amyloid substances in lung tissues. These amyloid deposits are not native to lung tissue and their accumulation may be associated with genetic factors, chronic inflammation, or tumors. Symptoms vary depending on the location and extent of deposition and may include cough, hemoptysis (coughing up blood), and dyspnea (difficulty breathing). Some patients may also have involvement of multiple organs throughout the body.

If you experience any lung-related symptoms, seek timely medical attention to determine the specific condition through imaging studies and pathological examinations. Regular follow-up evaluations are essential to monitor disease progression, adjust treatment strategies, and preserve lung function.