What are the side effects and contraindications of Xiqingguo Granules?

Side effects of Xiqingguo Granules may include gastrointestinal discomfort, allergic reactions, dizziness and headache, worsening of dry mouth or sore throat, and abnormalities in liver and kidney function. Contraindications include individuals with allergic constitutions, those with deficiency-cold of the spleen and stomach, diabetic patients, pregnant or breastfeeding women, and those with severe liver or kidney insufficiency. If severe discomfort or allergic symptoms occur after use, discontinue the medication immediately and seek medical attention promptly.

1. Side Effects

1. Gastrointestinal Discomfort: Nausea, vomiting, abdominal distension, and diarrhea may occur after taking the medication. These symptoms are usually caused by irritation of the gastrointestinal mucosa by the drug's components and are more likely to occur in individuals with weak spleen and stomach function. Mild symptoms typically resolve on their own.

2. Allergic Reactions: A small number of people may develop skin allergies such as rashes, itching, or redness. In severe cases, difficulty breathing may occur. The drug should be discontinued immediately and medical treatment sought.

3. Dizziness and Headache: Some patients may experience mild dizziness or headaches, which are generally related to the drug’s effect on the nervous system. These symptoms usually do not affect continued use, and resolve after discontinuation.

4. Worsening of Dry Mouth or Sore Throat: In rare cases, the medication may be inappropriate or incorrectly dosed, leading to aggravated symptoms of dry mouth or sore throat. The treatment plan should be adjusted promptly in such cases.

5. Liver and Kidney Function Abnormalities: Long-term or excessive use may increase the metabolic burden on the liver and kidneys, leading to abnormal liver or kidney function tests. Use with caution in individuals with pre-existing liver or kidney dysfunction.

2. Contraindications

1. Individuals with Allergic Constitutions: People prone to allergies may have a higher risk of allergic reactions to the drug's components and should avoid using this product.

2. Individuals with Deficiency-Cold of the Spleen and Stomach: The medicine has a relatively cold nature. Those with deficiency-cold of the spleen and stomach may experience worsened symptoms such as abdominal pain, diarrhea, and cold limbs after taking it, so its use is prohibited.

3. Diabetic Patients: Xiqingguo Granules contain sucrose, which may elevate blood glucose levels and interfere with glycemic control; therefore, diabetic patients should avoid using this product.

4. Pregnant and Breastfeeding Women: Safety data for this medication during pregnancy and lactation are insufficient. To prevent potential harm to the fetus or infant, pregnant and breastfeeding women should not use this product.

5. Patients with Severe Liver or Kidney Insufficiency: The drug is metabolized through the liver and kidneys. Using it in patients with severe liver or kidney insufficiency may further burden these organs and potentially worsen their condition; thus, use is prohibited.

During treatment, maintain a light diet and avoid spicy or greasy foods. Drink plenty of water to promote drug metabolism. Follow the dosage instructions on the label or as prescribed by a physician strictly—do not adjust the dose or extend the duration of use without guidance. If mild discomfort occurs, monitor symptoms closely and avoid concomitant use of other tonic herbal medicines.