Can chronic myeloid leukemia be cured?

Dec 12, 2025 Source: Cainiu Health

Dr. Li Feng

Introduction

Chronic myeloid leukemia (CML) can be clinically cured in some cases. Patients who meet the criteria have the chance of complete cure through hematopoietic stem cell transplantation. For those ineligible for transplantation, standardized targeted therapy can effectively control the disease long-term and maintain a normal quality of life. Daily care requires strict adherence to prescribed medication without擅自 adjusting dosages. Regular follow-up tests, including complete blood counts and bone marrow aspiration, are essential.

Chronic myeloid leukemia (CML) can be clinically cured in some patients. Those who meet the criteria may achieve complete cure through hematopoietic stem cell transplantation; for patients ineligible for transplantation, standardized targeted therapy can effectively control the disease long-term and maintain a normal quality of life.

Hematopoietic stem cell transplantation is currently a key approach to curing CML, especially suitable for younger patients with a matched donor. Successful reconstitution of hematopoiesis after transplantation can eliminate abnormal blood cells and achieve disease eradication. However, risks such as infection and graft rejection exist, requiring strict adherence to medical protocols for pre-transplant evaluation and post-transplant care.

Many patients are unable to undergo transplantation due to difficulties in finding a matched donor or advanced age. For these patients, targeted therapy is an effective alternative. Targeted drugs can precisely inhibit the proliferation of abnormal cells. Most patients achieve stable disease conditions or even deep molecular responses with medication, significantly prolonging survival, and some can return to normal work and daily life.

Daily management should emphasize taking medication regularly without adjusting dosage arbitrarily; regular follow-up tests such as complete blood counts and bone marrow aspiration are essential to monitor disease progression; maintaining dietary hygiene and preventing infections are also crucial.

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