Can people with thrombocytosis receive the quadrivalent vaccine?
Dec 12, 2025
Source: Cainiu Health
Dr. Li Feng
Introduction
In general, whether patients with thrombocytosis can receive the quadrivalent vaccine depends on the control status of their condition. Those with stable disease are usually eligible for vaccination, while those with uncontrolled disease or in an acute phase should not be vaccinated. To ensure vaccination safety, patients should clearly understand their disease status before vaccination and inform healthcare providers of their medical history and medication use in advance.
Generally, whether patients with thrombocytosis can receive the quadrivalent vaccine depends on the control status of their condition. Those with stable disease are usually eligible for vaccination, while those with uncontrolled disease or in an acute phase should avoid vaccination. The specific analysis is as follows:
If the patient's condition is stable, platelet count is maintained within a reasonable range, there are no significant symptoms such as bleeding or thrombosis, and there are no other contraindications to vaccination, then receiving the quadrivalent vaccine is feasible. In this case, vaccination will not exacerbate the underlying condition and can provide appropriate protective benefits.
If the patient’s condition is not well controlled, with elevated platelet counts or frequent episodes of bleeding or thrombosis, the body is in an unstable state. Vaccination under these circumstances may increase the risk of adverse reactions and could interfere with the assessment of disease progression; therefore, vaccination is not recommended.
To ensure vaccination safety, patients should clearly understand their disease status before vaccination and inform healthcare providers of their medical history and medication use in advance. After vaccination, they should remain under observation, routinely monitor platelet counts, and maintain healthy lifestyle habits to support disease stability and post-vaccination recovery.
