What Causes Uterine Fibroids?

Jul 08, 2026 Source: Cainiu Health
Dr. Zhang Lu
Introduction
In general, uterine fibroids may be caused by factors such as chronic sleep deprivation, a high-fat diet, pelvic inflammatory disease, endometrial hyperplasia, or adenomyosis. If you experience any discomfort or symptoms, it is advisable to seek timely medical evaluation and treatment at a reputable hospital. In daily life, maintain healthy sleep and dietary habits, consume a balanced diet to help regulate hormone levels, and practice proper genital hygiene to prevent gynecological infections.

Generally, uterine fibroids may be caused by factors such as chronic sleep deprivation, a high-fat diet, pelvic inflammatory disease (PID), endometrial hyperplasia, and adenomyosis. If uncomfortable symptoms arise, it is advisable to seek timely medical evaluation and treatment at a reputable hospital. A detailed analysis follows:

1. Chronic Sleep Deprivation

Chronic sleep deprivation disrupts the body’s endocrine rhythm, leading to estrogen secretion disorders that continuously stimulate abnormal proliferation of uterine smooth muscle. Establishing regular sleep-wake patterns, ensuring adequate rest, avoiding reversed day-night schedules, and maintaining endocrine stability are recommended.

2. High-Fat Diet

Long-term consumption of high-fat foods elevates endogenous estrogen levels, persistently stimulating the myometrium and promoting fibroid growth. Adopt a light, low-fat diet rich in fresh fruits, vegetables, and whole grains, while minimizing intake of fried and greasy foods.

3. Pelvic Inflammatory Disease (PID)

Chronic inflammation resulting from pathogen proliferation within the pelvis repeatedly stimulates the myometrium, causing localized abnormal tissue proliferation and subsequent fibroid formation. Antibiotics such as cefdinir dispersible tablets, tinidazole tablets, or azithromycin tablets may be prescribed per physician guidance. Maintain genital hygiene daily and avoid unprotected or unhygienic sexual activity.

4. Endometrial Hyperplasia

Hormonal imbalance triggers excessive endometrial proliferation; when this hyperplastic tissue extends into the myometrium, it can induce nodular changes and fibroid development. Under medical supervision, medications such as norethisterone tablets, progesterone capsules, or mifepristone tablets may be prescribed. In severe cases, hysteroscopic endometrial resection may be indicated.

5. Adenomyosis

In adenomyosis, ectopic endometrial tissue invades the myometrium; cyclic stimulation by this ectopic tissue leads to myometrial thickening and abnormal proliferation, thereby predisposing to secondary fibroid formation. Hormonal therapy—including gestrinone capsules, Guizhi Fuling capsules, or Sanjie Zhen Tong capsules—may be prescribed per physician guidance. For severe cases, laparoscopic myomectomy may be required.

In daily life, maintain healthy sleep and dietary habits, ensure balanced nutrition to regulate hormone levels, practice proper genital hygiene to prevent gynecological infections, and undergo routine gynecologic ultrasonography for early detection of uterine abnormalities.