What Are the Commonly Used Medications for Periarthritis of the Shoulder?

Sep 04, 2026 Source: Cainiu Health
Dr. Chen Jian
Introduction
Commonly used medications for periarthritis of the shoulder include celecoxib capsules, diclofenac sodium sustained-release tablets, ibuprofen gel, Huoxue Zhitong capsules, and flurbiprofen gel patches—available in both oral and topical formulations. If severe shoulder swelling and pain occur alongside complete immobility of the arm, localized skin warmth, or ulceration, prompt medical evaluation and treatment at a hospital are recommended.

Commonly used medications for shoulder periarthritis include celecoxib capsules, diclofenac sodium sustained-release tablets, ibuprofen gel, Huoxue Zhitong capsules (a traditional Chinese medicine formulation for promoting blood circulation and relieving pain), and flurbiprofen gel patches—available as both oral and topical agents. If severe shoulder swelling and pain occur alongside complete immobility of the arm, localized skin warmth or ulceration, prompt medical evaluation and treatment at a hospital are strongly recommended.

1. Celecoxib Capsules: An oral analgesic and anti-inflammatory medication that reduces inflammatory responses around the shoulder joint and alleviates associated pain. To minimize gastrointestinal irritation, take after meals and strictly adhere to the prescribed dosage. Monitor for any gastrointestinal or other systemic adverse reactions.

2. Diclofenac Sodium Sustained-Release Tablets: These inhibit the production of inflammatory mediators, thereby improving shoulder pain caused by periarthritis and reducing discomfort during joint movement. Due to their prolonged duration of action, dosage must not be increased arbitrarily. Individuals with compromised gastrointestinal function should closely monitor bodily responses following administration.

3. Ibuprofen Gel: A topical preparation applied directly to the skin over the painful shoulder area. The active ingredient penetrates the skin to exert its therapeutic effect, helping to relieve localized distending pain. Avoid application on broken or damaged skin; gently massage the area after application to enhance absorption and reduce systemic burden compared with oral medications.

4. Huoxue Zhitong Capsules: An oral traditional Chinese medicine formulation that improves local microcirculation in the shoulder region and alleviates distending pain caused by blood stasis. It also helps relax stiff periarticular soft tissues. During use, monitor gastrointestinal tolerance; this medication is contraindicated in individuals with bleeding tendencies.

5. Flurbiprofen Gel Patch: A topical patch applied directly to the painful shoulder area, providing continuous release of the active drug component. It effectively reduces pain associated with shoulder inflammation. Patients with sensitive skin should closely observe cutaneous reactions; if erythema or pruritus develops, promptly remove the patch to prevent allergic dermatitis.

Concurrently, incorporate appropriate shoulder-stretching exercises into your routine. Avoid maintaining a single posture for extended periods. Ensure adequate shoulder warmth and protect against direct exposure to cold drafts. Gradually increase shoulder joint mobility while minimizing load-bearing activities, thereby facilitating progressive functional recovery of the shoulder girdle.