What medications are used for lumbar intervertebral disc slippage?

Lumbar spondylolisthesis may be managed with oral medications—such as celecoxib capsules, diclofenac sodium sustained-release tablets, mecobalamin tablets, Yaobi Tong capsules, and eperisone hydrochloride tablets—as prescribed by a physician to alleviate associated discomfort. If symptoms such as abnormal bowel or bladder function or persistent lower-limb weakness or paralysis occur, prompt medical evaluation and treatment at a hospital are strongly recommended.

1. Celecoxib Capsules: An oral anti-inflammatory and analgesic medication that suppresses local inflammatory responses in the lumbar region, thereby reducing low back and leg pain caused by spondylolisthesis. To minimize gastrointestinal irritation, it should be taken after meals. Strict adherence to the prescribed dosage is essential, and patients should monitor for any gastrointestinal side effects during treatment.

2. Diclofenac Sodium Sustained-Release Tablets: These reduce inflammatory edema around the nerve roots and alleviate radiating pain in the lumbar region and lower limbs. Due to their prolonged duration of action, dosage must not be increased arbitrarily. Individuals with compromised gastrointestinal function should closely observe any bodily changes following administration.

3. Mecobalamin Tablets: A neurotrophic oral preparation that acts directly on damaged nerve roots to support normal neural metabolism. It helps relieve abnormal sensations such as numbness and paresthesia in the lower limbs. Consistent, long-term use is required, and improvement in limb numbness and discomfort should be monitored over time.

4. Yaobi Tong Capsules: A traditional Chinese patent medicine administered orally to promote blood circulation and Qi flow in the lumbar region and alleviate distending pain in the low back and legs caused by blood stasis. It improves discomfort associated with lumbar movement. Patients should monitor gastrointestinal tolerance during treatment; this medication is contraindicated in individuals with active bleeding disorders.

5. Eperisone Hydrochloride Tablets: An oral muscle relaxant that alleviates muscular tension and spasm in the lumbar and dorsal regions. It reduces traction-related low back pain resulting from muscle rigidity. Some patients may experience drowsiness after taking this medication; thus, extra caution is advised when performing tasks requiring high concentration.

Concurrently with pharmacotherapy, appropriate bed rest is recommended. Activities involving bending, heavy lifting, prolonged standing, or prolonged sitting should be minimized. Lumbar warmth and protection should be maintained, and sudden twisting or forceful lumbar movements should be avoided. Regular follow-up lumbar imaging is advised, and additional therapeutic interventions should be selected based on clinical progression to prevent symptom recurrence.