Emergency Medications for Ventricular Fibrillation
Ventricular fibrillation (VF) constitutes cardiac arrest. When a patient develops VF, they suddenly lose consciousness, exhibit absent pulsations in major arteries, and cease breathing within one minute. Initial resuscitation involves immediate external chest compressions. Once a defibrillator is available, deliver one shock without delay. Immediately after defibrillation, resume chest compressions and provide artificial ventilation, then reassess the rhythm after two minutes.
If VF persists, deliver a second shock promptly. After defibrillation, continue chest compressions and artificial ventilation, and administer intravenous epinephrine 1 mg (repeat every 3–5 minutes as needed). Reassess the rhythm after another two minutes.
If VF remains refractory, proceed with a third shock. Following defibrillation, continue chest compressions and artificial ventilation, and initiate antiarrhythmic therapy with either amiodarone or lidocaine. For amiodarone, administer an initial intravenous bolus of 300 mg; if ineffective, give a subsequent 150 mg bolus. For lidocaine, administer an initial intravenous bolus of 1.0–1.5 mg/kg; if required, a second dose of 0.5–0.75 mg/kg may be given intravenously.