What Should I Do About Hormone-Dependent Dermatitis?

Steroid-dependent dermatitis results from prolonged topical application of glucocorticoid ointments or cosmetic products containing corticosteroids, leading to impairment of the facial skin barrier and thinning of the stratum corneum. Clinical manifestations include folliculitis-like lesions, telangiectasia, hyperpigmentation, and hirsutism. The disease course is characterized by recurrent episodes.

The primary step in treating steroid-dependent dermatitis is complete discontinuation of glucocorticoids. Concurrently, oral medications—including hydroxychloroquine, compound glycyrrhizin tablets, vitamin C, and antihistamines—may be prescribed to alleviate cutaneous hypersensitivity and reduce erythematous reactions. Additionally, non-steroidal topical calcineurin inhibitors—such as tacrolimus ointment or pimecrolimus cream—can be applied.

Patients should routinely use medical-grade skincare products with moisturizing and soothing properties. These products are free of alcohol, fragrance, and preservatives, thereby facilitating skin barrier repair and permitting long-term use.