What should I do if my scrotum becomes increasingly inflamed, swollen, and develops pus?

Scrotal inflammation (scrotitis) is an inflammatory condition of the scrotum caused by bacterial infection, commonly due to pathogens such as Staphylococcus aureus or Pseudomonas aeruginosa. When the scrotum becomes increasingly swollen and develops purulent discharge, conditions such as scrotitis or epididymo-orchitis should be considered. So, what should one do if scrotal inflammation with pus and progressive swelling occurs? Below, we address this question.

What to Do for Scrotal Inflammation with Pus and Progressive Swelling

In general, antimicrobial drug therapy is recommended, supplemented when appropriate by topical treatments. Epididymo-orchitis refers to the inflammatory process affecting the testis or both the testis and epididymis following infection by pathogenic microorganisms—including Escherichia coli, Staphylococcus species, and others—and is typically managed with pharmacotherapy.

For scrotitis, pharmacotherapy—particularly broad-spectrum antibiotics—is commonly employed. Frequently used intravenous agents include ceftriaxone sodium for injection and cefotaxime sodium for injection, which generally produce rapid therapeutic effects via intravenous infusion. Topical treatment options include chitosan wound-protecting gel and medical chitin-based liquid dressings. For epididymo-orchitis, intravenous antimicrobial agents such as etimicin sulfate injection or levofloxacin injection may be selected.

Additionally, dietary recommendations include avoiding alcohol and spicy or irritating foods; maintaining a balanced, nutrient-rich diet; consuming ample fresh vegetables and fruits; ensuring adequate rest; and enhancing overall immunity.

We hope the above information is helpful to you.