What is flunarizine indicated for?

Mar 27, 2022 Source: Cainiu Health
Dr. Li Man
Introduction
In general, flunarizine is primarily used to treat neurological disorders, including cerebral hypoperfusion, vertebral artery insufficiency, and post-stroke sequelae (e.g., improvement of associated signs and symptoms following cerebral thrombosis). It is also indicated for the management of tinnitus and migraine prophylaxis. Additionally, flunarizine may improve renal function and can be used in chronic renal failure.

Flunarizine alleviates cerebral vasospasm, improves cerebral blood circulation, and increases cerebral blood supply. It is highly effective in treating headache, dizziness, and other symptoms caused by cerebrovascular diseases. Additionally, it is used for both the treatment and prophylaxis of migraine. So, what conditions is flunarizine primarily indicated for? The following section addresses this question.

Primary Indications for Flunarizine

Generally, flunarizine is mainly used to treat neurological disorders. It is indicated for cerebral hypoperfusion, vertebrobasilar insufficiency, and for improving clinical signs following cerebral thrombosis. It is also used in the management of tinnitus and for migraine prophylaxis. Moreover, flunarizine may improve renal function and can be used in chronic renal failure.

Additionally, flunarizine blocks pathological calcium overload in neurons, thereby preventing paroxysmal depolarization and subsequent epileptic seizures. It also exerts vestibular inhibitory effects and enhances blood flow in the cochlear small arteries, thereby improving circulation to the vestibular organs.

However, caution is warranted: common adverse effects include somnolence and fatigue. With prolonged use, depression may occur. Extrapyramidal symptoms—including akinesia, oromandibular dystonia, and rigidity—may also develop during treatment. If any of the above adverse reactions occur, or if any discomfort arises during therapy, patients should seek immediate medical attention.

We hope the above information is helpful to you.

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