Can diammonium glycyrrhizinate enteric-coated capsules protect the liver?

The liver functions much like a central bank, regulating the circulation of the body’s three major “currencies.” Emotions, sleep, diet, and even medications can all influence the liver’s function of smoothing and regulating Qi flow. “Liver protection,” as the term implies, refers to safeguarding liver health. So, can diammonium glycyrrhizinate enteric-coated capsules protect the liver? Below, we address this question.

Can Diammonium Glycyrrhizinate Enteric-Coated Capsules Protect the Liver?

Diammonium glycyrrhizinate enteric-coated capsules are commonly prescribed, primarily for treating acute and chronic hepatitis accompanied by elevated transaminase levels. These capsules possess hepatoprotective, liver-nourishing, and transaminase-lowering effects. The primary pharmacological actions of diammonium glycyrrhizinate are hepatoprotection and reduction of serum transaminases. In patients experiencing acute hepatitis flare-ups, oral administration of diammonium glycyrrhizinate effectively lowers aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels.

Diammonium glycyrrhizinate enteric-coated capsules are extracted from licorice root and exhibit potent anti-inflammatory activity—distinct from antibiotic-mediated anti-inflammatory effects. This anti-inflammatory action refers specifically to the drug’s ability to promote hepatic metabolism and biochemical transformation. Additionally, it helps preserve normal liver function, protects hepatocytes, and reduces transaminase levels, with well-documented clinical efficacy.

Knowledge Extension: Precautions for Using Diammonium Glycyrrhizinate Enteric-Coated Capsules

1. Always use diammonium glycyrrhizinate enteric-coated capsules strictly as prescribed by a physician; self-medication is not advised.

2. Elderly patients with underlying conditions—particularly those with hypertension—should generally avoid using diammonium glycyrrhizinate enteric-coated capsules, as they may cause elevated blood pressure. Prolonged use in hypertensive patients could exacerbate hypertension; therefore, oral administration of this medication is not recommended for individuals with hypertension.

3. Patients with renal failure must not take diammonium glycyrrhizinate enteric-coated capsules.

4. Since diammonium glycyrrhizinate enteric-coated capsules may disrupt serum electrolyte balance—such as causing abnormal serum potassium or sodium concentrations—patients undergoing long-term treatment should undergo regular monitoring of serum electrolytes to prevent electrolyte imbalances.

The above provides an overview of whether diammonium glycyrrhizinate enteric-coated capsules offer hepatoprotection. We hope this information proves helpful to you.