What should I do if one testicle is larger than the other?

In daily life, some men may have one testicle noticeably larger than the other—either due to genetic factors or acquired causes—leading to significant self-consciousness or feelings of inferiority. What should be done if the testicles are markedly asymmetrical in size?

What to Do When Testicles Are Asymmetrical in Size

Men with visibly asymmetrical testicles should seek medical evaluation, including physical examination and scrotal ultrasound, to assess whether both testicles have developed normally. Several possibilities exist: - The larger testicle may be inflamed; in such cases, anti-inflammatory treatment is indicated. - The smaller testicle may reflect either congenital hypoplasia or acquired atrophy. A serum sex hormone panel should be performed to evaluate testicular function. If hormonal abnormalities or testicular atrophy are confirmed, intramuscular gonadotropin therapy may be administered to stimulate testicular development. In cases of irreversible testicular necrosis or severe atrophy, surgical removal of the affected testicle may be necessary.

It is normal for testicles to differ slightly in size. Generally, as long as each testicle measures ≥15 mL in volume, their functional capacity remains comparable. Marked size asymmetry may indicate unilateral underdevelopment (i.e., reduced size on one side) or inflammation-induced enlargement on the contralateral side. If no pain or other discomfort is present and reproductive/endocrine function remains unaffected, mild asymmetry is considered physiologic. However, if obvious abnormalities are noted, scrotal ultrasound is recommended to identify the underlying cause—and timely intervention should be pursued when indicated.

Maintain good local hygiene and change underwear regularly. We hope this information is helpful to you.