What are the dermatological symptoms of Candida glabrata infection?

In daily life, exposure to damp living or working environments may lead to eczema. What are the dermatological symptoms of Candida glabrata infection?

What Are the Dermatological Symptoms of Candida glabrata Infection?

Candida glabrata infection is a type of fungal skin infection. Its most common clinical manifestation is various forms of skin rashes, particularly among individuals who frequently work in humid conditions. Lesions typically occur in skin folds—such as the groin, buttocks, axillae, and under the breasts—with well-defined borders. The affected areas appear moist and often exhibit erosion; the base is erythematous, while the periphery commonly displays scaling. Scattered peripheral lesions may include erythematous macules, papules, vesicles, or pustules. Some rashes present as flat, dark-red papules (approximately绿豆-sized, i.e., ~2–3 mm in diameter), with clear margins and overlying grayish-white, scaly desquamation. Concurrently, patients may develop candidal angular cheilitis or oral candidiasis. Direct microscopic examination reveals pseudohyphae and blastospores; the presence of hyphae indicates active pathogenicity.

Vaginal or vulvar pruritus may also occur in C. glabrata infection. In some cases, vaginal dysbiosis develops, resulting in increased vaginal discharge, foul odor—or even a strong, unpleasant smell—and occasionally “cottage cheese–like” discharge. Vaginal pain may also be present.

Antifungal treatment is recommended for approximately two weeks, followed by follow-up evaluation. We hope this information is helpful to you.