What does an eGFR (CKD-EPI) value greater than 90 mL/min/1.73 m² mean?
Apr 28, 2022
Source: Cainiu Health
Dr. Zhao Xinju
Introduction
eGFR (CKD-EPI) > 90 mL/min indicates a glomerular filtration rate greater than 90 mL/min, which is generally considered normal. This value is influenced by numerous factors, including age and sex—eGFR is typically approximately 10% lower in females than in males. The normal eGFR range for adult males is 110–140 mL/min, while for children it is 80–120 mL/min.
An eGFR (CKD-EPI) value greater than 90 mL/min/1.73 m² indicates a glomerular filtration rate (GFR) exceeding 90 mL/min/1.73 m², which is generally considered normal. Details are as follows:
The normal reference range for eGFR is 90–120 mL/min/1.73 m². eGFR stands for estimated glomerular filtration rate—a functional indicator of kidney health calculated using the CKD-EPI equation. This equation incorporates serum creatinine levels along with variables such as body weight, sex, and age. eGFR is a clinically reliable marker for assessing GFR and provides a relatively accurate evaluation of overall renal function. According to international guidelines, a declining eGFR often signals impaired kidney function.
However, eGFR values are influenced by numerous factors—including age and sex. For instance, eGFR in females is typically ~10% lower than in males. The normal GFR range for adult males is 110–140 mL/min/1.73 m², whereas for children it is 80–120 mL/min/1.73 m². After age 40, GFR declines progressively—by approximately 10% per decade—and by age 80, GFR may have decreased by roughly 40% compared to baseline.
