What drugs can increase the glomerular filtration rate (GFR)?

       Numerous medications can enhance the glomerular filtration rate (GFR), and the choice of drug should be tailored to the underlying cause. A reduced GFR is commonly associated with either acute kidney injury (AKI) or chronic kidney disease (CKD). Specific scenarios are outlined below:

       1. Acute Kidney Injury (AKI)

       AKI refers to a rapid decline in renal function resulting from various etiologies. Clinical manifestations include decreased GFR and accumulation of nitrogenous waste products. Management involves controlling infection, maintaining fluid and electrolyte balance, and, under physician guidance, administering oral medications such as amoxicillin tablets, cefpirin hydrochloride tablets, furosemide tablets, or torasemide tablets to improve GFR.

       2. Chronic Kidney Disease (CKD)

       Renal vascular lesions are a major contributor to CKD; conditions such as hypertension and diabetes mellitus can induce these vascular changes, ultimately leading to a reduced GFR. Under medical supervision, patients may take medications including febuxostat tablets and sodium bicarbonate tablets. Additionally, patients should adhere to dietary modifications—avoiding irritant foods—and maintain adequate hydration and frequent urination to support metabolic clearance.