Normal Parathyroid Hormone (PTH) Levels

May 11, 2022 Source: Cainiu Health
Dr. Pan Yongyuan
Introduction
The normal reference range for parathyroid hormone (PTH) is 0–70 pg/mL. PTH is an endogenous hormone produced by the parathyroid glands—small endocrine glands located adjacent to the thyroid gland. It plays a key regulatory role in maintaining homeostasis of calcium and phosphorus ions, as well as other nutrients, in the body. Measuring PTH levels in laboratory tests not only helps effectively assess whether a patient has disorders of the parathyroid system but also guides targeted, systemic treatment strategies.

Parathyroid hormone (PTH) primarily regulates calcium and phosphorus metabolism in the body to maintain serum calcium concentration—specifically, it promotes an increase in serum calcium levels and a decrease in serum phosphorus levels. So, what is the normal reference range for parathyroid hormone?

Normal Reference Range for Parathyroid Hormone

The normal reference range for parathyroid hormone is 0–70 pg/mL. PTH is an endogenous hormone produced by the parathyroid glands, which are located adjacent to the thyroid gland. It exerts regulatory effects on calcium ions, phosphate ions, and other nutrients in the body. Laboratory measurement of PTH levels not only helps effectively assess whether a patient has disorders of the parathyroid or thyroid systems but also facilitates targeted, systemic treatment. Elevated PTH levels beyond the normal range may indicate conditions such as hyperparathyroidism or other parathyroid-related disorders.

The normal reference range for parathyroid hormone is below 70 pg/mL. PTH primarily regulates calcium and phosphorus metabolism in vertebrates, promoting elevated serum calcium and reduced serum phosphorus levels. Its principal target organs are bone and kidney; it also indirectly enhances intestinal absorption of Ca²⁺. Common detection methods include chemiluminescent immunoassay (CLIA), radioimmunoassay (RIA), and enzyme-linked immunosorbent assay (ELISA).

Parathyroid hormone secretion is regulated by serum calcium concentration: elevated serum calcium inhibits PTH secretion, whereas decreased serum calcium stimulates its secretion. We hope this information is helpful to you!