What medications are most effective for treating uterine fibroids?

Uterine fibroids are benign tumors; therefore, asymptomatic patients generally require no treatment. Women with mild symptoms may undergo pharmacological therapy. Uterine fibroids are primarily attributed in Traditional Chinese Medicine (TCM) to deficiencies in qi and blood, as well as stagnation of damp-heat—conditions that are difficult to resolve completely with conventional medications. Thus, TCM-based herbal therapy is commonly employed for treating uterine fibroids, offering a holistic approach that addresses both the root cause and manifesting symptoms. Although therapeutic effects may not be immediate, this approach provides excellent overall regulation and conditioning of the body.

Additionally, patients may receive gonadotropin-releasing hormone (GnRH) agonists tailored to their specific clinical situation. Commonly used agents in clinical practice include triptorelin, leuprolide, and goserelin. Other options include mifepristone, tamoxifen, and androgenic agents such as methyltestosterone and testosterone propionate, all of which help suppress tumor growth.

However, it is essential to emphasize that these medications must be administered strictly under medical supervision to avoid potential disease exacerbation.