How many doses of the 23-valent pneumococcal vaccine are required?

Pneumonia is highly prevalent. To effectively prevent it, vaccination is the first and most important step. However, several vaccines are available to prevent pneumonia, leaving many people uncertain about which one to choose. In current medical practice, many individuals opt directly for the 23-valent pneumococcal vaccine. So, how many doses of the 23-valent pneumococcal vaccine are required?

How Many Doses of the 23-Valent Pneumococcal Vaccine Are Required?

A single dose of the 23-valent pneumococcal vaccine is sufficient. This vaccine provides coverage against 23 serotypes of Streptococcus pneumoniae, which are commonly responsible for pneumococcal infections; approximately 90% of pneumococcal pneumonia cases are caused by these 23 serotypes. Protective antibodies against all or most of these pneumococcal serotypes typically develop within 2–3 weeks after vaccination. The vaccine is generally suitable for children aged two years and older, children with recurrent pneumonia, and high-risk populations. Post-vaccination protection efficacy exceeds 92%, with a favorable safety profile and robust immune response lasting up to five years.

For individuals who have already received a pneumococcal vaccine, routine revaccination is not recommended. However, revaccination may be advised for high-risk groups—such as those who underwent splenectomy more than five years ago and previously received pneumococcal vaccination, or those whose antibody titers have significantly declined (e.g., patients with nephrotic syndrome, renal failure, or organ transplantation). Thus, while a single dose is generally recommended for most individuals, revaccination after five years may be considered in special circumstances—for example, in highly susceptible individuals with low antibody titers or in high-risk populations with compromised immunity.

After receiving the 23-valent pneumococcal vaccine, avoid spicy, stimulating foods and seafood. Ensure adequate rest, avoid staying up late, and maintain a positive mood. Monitor the injection site for induration or swelling, and refrain from bathing on the day of vaccination. We hope this information is helpful to you.