When is the latest time to administer the first dose of the Japanese encephalitis attenuated vaccine?

The live attenuated Japanese encephalitis (JE) vaccine is primarily intended for the prevention of JE in young children. “JE vaccine” is a general term encompassing several types of vaccines. So, by when should the first dose of the live attenuated JE vaccine be administered?

Latest Recommended Timing for the First Dose of the Live Attenuated JE Vaccine

The live attenuated JE vaccine is included in China’s national immunization program. Its primary purpose is early prevention of encephalitis caused by Japanese encephalitis virus infection. This vaccine effectively stimulates the body to produce protective antibodies, offering excellent immunogenicity and long-lasting protection. Typically, two doses are required, with an interval of approximately one year between them, to minimize potential adverse effects on children’s health.

According to national guidelines, the inactivated JE vaccine requires a primary immunization series of two doses: the first dose may be administered to infants aged six months or older, followed by the second dose 7–10 days later. Booster doses are recommended at 18–24 months of age, at age 4 years, and again at age 6 years. In contrast, the live attenuated JE vaccine schedule recommends the first dose at age 1 year, a booster dose at age 2 years, and another booster at age 7 years.

Children aged eight months or older—typically around one year of age—are generally eligible to receive the live attenuated JE vaccine. However, age-eligible children should be vaccinated according to local epidemiological conditions or as mandated by local government health authorities. Wishing you good health and happiness!