Can evening primrose oil soft capsules be taken long-term?

Evening primrose oil capsules are generally not intended for long-term use.

In clinical practice, evening primrose oil capsules effectively alleviate constipation by promoting gastrointestinal motility and facilitating bowel movements. They also possess anticoagulant, lipid-lowering, and endocrine-regulating properties, making them a commonly prescribed medication. However, prolonged use is not recommended, as it may lead to drug dependence or cause gastrointestinal dysfunction—potentially resulting in diarrhea and abdominal pain. Therefore, evening primrose oil capsules should only be taken under the guidance of a physician; self-medication must be avoided.

Evening primrose oil capsules also enhance fat metabolism and are frequently used clinically as an adjunct for weight management. Nevertheless, regardless of the desired therapeutic effect, long-term use is contraindicated to prevent adverse reactions.

Additionally, evening primrose oil capsules exhibit antiplatelet aggregation activity. Consequently, they are contraindicated in individuals with bleeding disorders or in pregnant women, as their use may precipitate severe hemorrhage—potentially life-threatening in serious cases.