The most serious adverse effect of sulfonylurea antidiabetic agents

Dec 28, 2021 Source: Cainiu Health
Disease description:

My grandmother has diabetes and is taking sulfonylurea antidiabetic drugs, but she is concerned about potential side effects. What is the most serious adverse effect associated with sulfonylureas?

Doctor's answer (2)
Dr. Zhao Lianli
Given the potential for hepatic injury, antidiabetic medications are generally associated with minimal systemic toxicity and adverse effects while remaining clinically effective. However, in cases of severe diabetes where oral medications fail to achieve adequate glycemic control, patients may require long-term insulin injections. Additionally, patients must strictly adhere to a dietary regimen that excludes high-sugar foods.