Efficacy and Actions of Fluorouracil Ointment
Disease description:
Meanwhile, she was recently diagnosed with breast cancer. Today, I accompanied her to the hospital, where the doctor prescribed fluorouracil ointment. I would like to know the drug’s pharmacological effects and clinical uses.
Doctor's answer (1)
Dr. Wang Bingping
Fluorouracil ointment inhibits thymidylate synthase and blocks the conversion of deoxyuridine monophosphate to thymidine monophosphate, thereby interfering with DNA synthesis. It is primarily used to treat breast cancer, colorectal cancer, and skin cancer, and effectively alleviates basal cell carcinoma of the skin. Additionally, it may be used to relieve severe psoriasis symptoms.
