What does it mean when serum alanine aminotransferase (ALT) is elevated?

Sep 21, 2020 Source: Cainiu Health
Disease description:

I went for a checkup this week and had blood tests done. The report shows elevated serum alanine aminotransferase (ALT). I would like to ask my doctor: What does elevated serum alanine aminotransferase indicate?

Doctor's answer (2)
Dr. Li Qinghui
Hello, elevated serum alanine aminotransferase (ALT) levels are commonly observed in hepatobiliary diseases—for instance, liver injury, particularly in viral hepatitis. Chronic or recurrent infection can cause mild damage to hepatocytes, leading to increased ALT levels. Biliary system disorders—such as common bile duct stones and recurrent cholecystitis causing cholestasis—can also elevate transaminase levels. Additionally, certain medications may induce hepatic injury, and occasionally, intense, high-intensity physical exercise can result in elevated transaminases. We hope the above information is helpful to you. Wishing you a happy and healthy life!