Will systemic lupus erythematosus (SLE) be inherited by children born to affected mothers?

Apr 21, 2022 Source: Cainiu Health
Disease description:

I have systemic lupus erythematosus (SLE) and am planning to have a child. I’m concerned about the possibility of passing it on genetically—will SLE be inherited by my child?

Doctor's answer (1)
Dr. Gan Liqiang
Having children when suffering from systemic lupus erythematosus (SLE) may involve a genetic risk. SLE is an autoimmune connective tissue disease; its exact cause remains unclear but is thought to involve genetic factors, immune system dysregulation, and hormonal imbalances. Consequently, there is a potential for SLE to be inherited by offspring. A family history of SLE warrants special attention.