What medications can be taken for irritability and anger during menopause?

Apr 21, 2022 Source: Cainiu Health
Disease description:

I’ve entered menopause and am constantly feeling irritable and angry. I’d like to take medication for relief—what medications are recommended for irritability and anger during menopause?

Doctor's answer (1)
Dr. Luo Li
Irritability and mood swings during menopause can generally be treated with hormone replacement therapy (HRT) under a physician’s guidance. In clinical practice, estrogen—such as estradiol or estradiol valerate—is commonly prescribed. These medications help restore ovarian function and improve mood, thereby alleviating irritability and anger. Alternatively, paroxetine hydrochloride may be prescribed per medical advice to address psychiatric symptoms and relieve irritability and mood instability.