Are there any risks associated with commonly used glycerin suppositories?

Frequent use of glycerin suppositories can cause intestinal wall dryness. Glycerin suppositories stimulate the intestinal wall to trigger the defecation reflex and facilitate bowel movements; however, overuse may lead to excessive stimulation of the rectum, reducing its sensitivity. This can result in habitual constipation and dependence on the suppository. Moreover, glycerin suppositories may cause intense local tissue contraction and chronic inflammation. Therefore, it is essential to use them appropriately, establish regular bowel habits, and consume foods high in dietary fiber to promote gastrointestinal motility.