Will taking ibuprofen during menstruation lead to drug resistance?

Jul 26, 2022 Source: Cainiu Health
Disease description:

I usually take ibuprofen for dysmenorrhea, about once or twice per menstrual cycle. Could regular use of ibuprofen during menstruation lead to drug resistance?

Doctor's answer (1)
Dr. Lv Aiming
Taking ibuprofen during menstruation may lead to drug tolerance. If you experience lower abdominal discomfort during your period, you may take ibuprofen sustained-release capsules orally for symptom relief. Additionally, applying a warm compress to the abdomen can improve local blood circulation and help alleviate dysmenorrhea. To effectively manage dysmenorrhea, it is essential to visit a hospital for a comprehensive evaluation to identify the underlying cause and receive targeted treatment. Moreover, long-term use of ibuprofen inevitably increases the risk of developing drug tolerance.