Can cold sores on the lips infect the penis?

Cold sores on the lips generally do not transmit to the penis. Cold sores are typically caused by herpes simplex virus type 1 (HSV-1), whereas genital herpes is primarily caused by herpes simplex virus type 2 (HSV-2). Following onset, the condition is characterized mainly by clustered vesicles. Treatment may include topical application of acyclovir ointment, as directed by a physician.