What causes dysfunctional uterine bleeding during the perimenopausal period?

Oct 11, 2022 Source: Cainiu Health
Disease description:

Suffering from dysfunctional uterine bleeding, after taking dydrogesterone tablets for 5 days, the bleeding suddenly increased significantly. Want to know the causes of dysfunctional uterine bleeding during perimenopause?

Doctor's answer (1)
Dr. Mei Quan
Dysfunctional uterine bleeding during the perimenopausal period is generally caused by a decline in ovarian hormones. During this phase, ovarian hormone levels progressively decrease as ovarian function begins to diminish, resulting in the loss of feedback regulation on the hypothalamic-pituitary axis. This process is also related to local endometrial factors. After patients develop symptoms of the condition, they require medical evaluation followed by appropriate treatment.