Any cause can lead to bone hyperostosis.

Bone spurs may develop due to osteoarthritis, which causes joint damage and leads to the formation of bony projections. They can also result from natural aging of the joints and changes in joint mechanics associated with advancing age. Additionally, repeated stimulation leading to continuous bone spur formation or having autoimmune diseases may contribute to such overgrowths. Moreover, conditions such as being overweight or experiencing excessive joint strain may also trigger the development of bone spurs.