What does high creatinine mean after kidney transplantation?

Nov 14, 2022 Source: Cainiu Health
Disease description:

My grandfather had a kidney transplant surgery. When we went for a follow-up today, the doctor said his creatinine level was a bit high. Could you please explain what might be causing this?

Doctor's answer (1)
Dr. Zhao Xinju
High creatinine levels after kidney transplantation may be due to recent inadequate nutritional intake, leading to malnutrition and a slowed metabolic rate, which significantly reduces creatinine clearance. It could also result from hydronephrosis, which affects the patient's kidney function. Additionally, if the patient experiences a rejection reaction, causing the transplanted kidney to fail to function properly, this can also lead to elevated creatinine levels.