How is congenital funnel chest formed?

Nov 14, 2022 Source: Cainiu Health
Disease description:

After the baby was born, congenital funnel chest was detected. I'm a bit confused because all prenatal examinations during pregnancy were normal. I would like to know how congenital funnel chest develops.

Doctor's answer (1)
Dr. Chen Qirui
Congenital funnel chest may be caused by congenital factors, usually due to an imbalance between cartilage growth-promoting genes and growth-inhibiting genes during the embryonic period, leading to abnormal remodeling of anterior chest cartilage. It may also result from acquired factors, such as congenital diaphragmatic hernia or bronchopulmonary dysplasia.