Is leg fatigue and soreness in the right leg a precursor to leukemia?

Dec 22, 2022 Source: Cainiu Health
Disease description:

Recently, I've frequently felt soreness and fatigue in my right leg, which is very uncomfortable. A friend of mine was recently diagnosed with leukemia, so I'd like to ask whether soreness and fatigue in the right leg could be a precursor to leukemia?

Doctor's answer (1)
Dr. Zhang Heyang
Leg fatigue or soreness in the right leg is not necessarily a precursor to leukemia. Although some patients may experience symptoms such as general weakness and leg soreness after developing leukemia, not all cases of right leg discomfort are caused by leukemia. This symptom could instead result from excessive physical labor leading to muscle fatigue, or it might be due to anemia.