Why perform immunohistochemistry?

Mar 11, 2023 Source: Cainiu Health
Disease description:

Hello doctor, I have a relative whose child has been diagnosed with medulloblastoma. The doctor said immunohistochemistry is needed. I'd like to ask, what is immunohistochemistry, and why is it necessary?

Doctor's answer (1)
Dr. Liu Aihua
Immunohistochemistry is a molecular biology technique used to study the distribution and interactions of specific proteins and other macromolecules within cells or tissues. Research in immunohistochemistry is crucial for our deeper understanding of cancer, as it helps clarify the specific mechanisms involved in apoptosis, cell proliferation, and cancer development. Immunohistochemistry also enables us to investigate the effects of exogenous substances such as nutrients, bacteria, and viruses on cells. Moreover, immunohistochemistry can aid in studying disease progression and evaluating the effectiveness of new treatments. Experiments using immunohistochemistry help identify novel proteins and other macromolecules, and clarify how these proteins function during disease processes. Additionally, immunohistochemistry may assist in discovering new therapeutic approaches for treating specific diseases such as cancer and cardiovascular disorders. Therefore, immunohistochemistry is an important medical technique that helps us study and interpret pathological processes and supports the discovery of more effective treatments.