What Is the Difference Between Bactroban and Erythromycin Ointment?

Jun 30, 2021 Source: Cainiu Health
Disease description:

My skin was previously dry and cracked, accompanied by itching. I used Bactroban (mupirocin ointment) for several days with no improvement, but after applying erythromycin ointment for just one day, my symptoms resolved. Could you please explain the differences between these two medications?

Doctor's answer (1)
Dr. Liu Wan
Hello, both medications are topical antibiotics. Erythromycin ointment is white and is commonly used for its anti-inflammatory and antibacterial effects; it is effective in treating conditions such as acne, hemorrhoids, burns, and abscesses. Bactroban (mupirocin) is particularly effective for folliculitis and wound infections, and it exhibits strong skin penetration. Erythromycin is primarily active against Gram-positive bacteria, whereas Bactroban targets Gram-positive cocci—including *Staphylococcus aureus*. I hope this information is helpful. Wishing you good health!