Is neurofibroma serious?

The severity of neurofibromatosis varies among individuals and depends on disease progression, but it generally does not belong to particularly severe diseases. 1. Etiology and Classification: Neurofibromatosis (NF) is an autosomal dominant genetic disorder, classified into Type I (NF1) and Type II (NF2), mainly caused by mutations in genes on chromosome 22, which may lead to multi-system damage. 2. Clinical Manifestations: The main manifestations include café-au-lait spots on the skin and neurofibromas. Some patients may develop the disease due to long-term heavy smoking or genetic factors. 3. Treatment Methods: They include drug therapy, surgical treatment, and radiotherapy. Most neurofibromas are benign and can be effectively controlled with appropriate treatment. Patients generally have a good prognosis if the disease is detected timely, treated properly, and if there is no serious organ failure or malignant transformation.