What causes rhabdomyolysis?
Disease description:
After my husband worked out, he experienced muscle pain, swelling, and weakness. The hospital diagnosed him with rhabdomyolysis. I would like to know, what causes rhabdomyolysis?
Doctor's answer (1)
Dr. Xu Shuai
Rhabdomyolysis, also known as muscle dissolution syndrome, has various causes, primarily including the following:
1. Hereditary myopathies: Gene mutations lead to abnormal muscle structure and function, which can result in muscle dissolution.
2. Neurogenic muscle atrophy: Damage to the nervous system leads to prolonged lack of proper muscle activity, causing disuse atrophy, which exacerbates muscle injury and may lead to dissolution.
3. Metabolic myopathies: Metabolic disorders such as glycogen storage diseases and mitochondrial myopathies cause insufficient energy supply to muscles, leading to muscle dissolution.
4. Autoimmune myositis: The body's immune system mistakenly attacks muscle tissue, causing destruction and dissolution of muscle cells.
5. Drug side effects: Certain medications may interfere with normal muscle cell metabolism, leading to muscle injury and dissolution.
The specific cause must be determined based on the patient's individual circumstances and a physician's diagnosis.
