What should I do if toothache persists despite taking painkillers?

When tooth pain persists despite taking painkillers with unsatisfactory effect, the following measures may be considered: 1. Increase dosage or switch medication as directed by a physician: For non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, if the pain relief is inadequate after administration, the dosage may be appropriately increased under a doctor's guidance. However, it should be noted that certain medications have a "ceiling effect," meaning that beyond a certain dosage, increasing the amount will not enhance analgesia but may instead increase the risk of adverse reactions. If the maximum recommended dosage has already been reached without effect, switching to a more potent analgesic may be considered. 2. Combine with other treatment modalities: When pharmacological treatment alone proves insufficient, adjunctive therapies such as physical therapy, acupuncture, or massage may be employed. Alternatively, minimally invasive procedures such as nerve blocks or radiofrequency ablation may be considered to help alleviate the pain. 3. Seek prompt medical attention: If the toothache persists, it is important to see a healthcare provider as soon as possible to determine the underlying cause and receive appropriate professional treatment, such as root canal therapy. Additionally, avoid consuming excessively hard or cold foods to prevent exacerbation of the pain.