The first-line drug for the treatment of chronic myeloid leukemia
Disease description:
My grandfather has had chronic myeloid leukemia for three years and has been taking medication continuously, but his condition has not improved. What is the first-line medication for treating chronic myeloid leukemia?
Doctor's answer (1)
Dr. Liu Feng
The first-line drugs for treating chronic myeloid leukemia are primarily tyrosine kinase inhibitors (TKIs), which can effectively inhibit cell proliferation and improve disease symptoms.
Specifically, first-generation imatinib is the drug of choice and is suitable for low-risk elderly patients. For younger, high-risk patients, second-generation nilotinib is often selected, as it enables patients to rapidly achieve deep remission. Additionally, second-generation dasatinib is commonly used in patients with kinase domain mutations.
These drugs demonstrate favorable performance in terms of safety, precision, and adverse reactions; however, their specific use should follow medical advice, and individualized treatment should be emphasized.
