What causes leukopenia (reduced white blood cell count)?

Jun 30, 2024 Source: Cainiu Health
Disease description:

Today, my company asked us to go to the hospital for a medical checkup. When I received my test report, I found out that it indicated I have leukopenia (reduced white blood cell count). May I ask what could cause a decrease in white blood cell count?

Doctor's answer (1)
Dr. Liu Feng
Leukopenia (reduced white blood cell count) can be caused by various factors, primarily summarized as follows: 1. Disease factors: Viral infections such as influenza, chickenpox, and viral hepatitis may lead to excessive consumption or destruction of white blood cells. 2. Medication effects: Long-term use of antibiotics, anticancer drugs, and certain other medications may destroy white blood cells, leading to a decreased count. 3. Immune system abnormalities: Autoimmune disorders such as systemic lupus erythematosus (SLE) can cause immune system dysfunction, resulting in reduced white blood cell counts. 4. Radiation exposure: Frequent exposure to radiation, such as from X-ray examinations, may damage hematopoietic stem cells and the bone marrow microcirculation, leading to leukopenia. The causes of leukopenia are diverse and must be evaluated based on the individual patient's condition. Prompt medical consultation is essential.